New obesity drug could result in weight loss of two stone in six months – Independent.ie

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The drug, researched in Ireland, could be another means to tackling obesity
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Laura Lynott

A new obesity drug found to reduce body weight by 11pc can result in weight loss of two stone within six months, a study has found.
The drug, researched in Ireland, could be another means to tackling obesity, a major health problem in this country.
The drug Cagrilintide works by increasing the sense of ‘satiety’ to allow those taking the treatment to feel less hungry and as a result, eat less.
It was trialled internationally in 10 countries on 706 patients, including participants in Ireland, with a group receiving the active treatment and another control group receiving a placebo.
Injected once a week, the treatment was found to achieve up to an 11pc reduction in body weight, or roughly two stone, in a study over six months, according to the Lancet.
Obesity Specialist at St Vincent’s University Hospital, Professor Carel le Roux, said: “Cagrilintide is a new medication which works by inducing fullness after a meal.
“Researchers at St Vincent’s Hospital worked with international colleagues to assess effects on bodyweight, safety and tolerability in patients with obesity.
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“Those receiving the highest doses of the medication lost 10.8pc of their weight, which is close to two stone for most people.
“A third of patients receiving it reported mild nausea, but this was usually moderate.”
Vera Vaughan from Dublin, who participated in the trial, felt there was a major need for the new drug and others like it to be made available to those living with obesity in Ireland.
“The Government should support more clinical research in Ireland to allow patients like me to benefit first from these innovations. This medication is life-changing,” she added.
Obesity affects more than a million people in Ireland and is one of the major causes of cancer, heart attacks and a reduction in quality of life.
It is the major contributing factor to type 2 diabetes which affects 200,000 people.
Treatment for type 2 diabetes alone accounts for more than 10pc of the overall healthcare budget.
In July, EU statistics agency, Eurostat, found Ireland has the second highest rate of obesity in the EU.
That study found 26pc of Irish adults were obese in 2019, far ahead of the EU average of 16pc. Only Malta was ahead with 28pc. In a similar study in 2014, Ireland was ranked seventh with an obesity rate of 18pc.
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